Section 1: Identification
Name: FAMOTIDINE
Uses:
- MEDICATION **QC REVIEWED**
Section 2: Hazard(s) Identification
Signal Word(s):
Warning
Section 3: Composition/Information on Ingredients
Name: FAMOTIDINE
CAS Registry Number: 76824-35-6
UNII: 5QZO15J2Z8
Synonyms:
- [Amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene] sulfamide[USP Convention. The United States Pharmacopeia 23/NF18. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates), p. 651]
- Propanimidamide, N'-(aminosulfonyl)-3-[[[2-[(diaminomethylene)amino]-4-thiazoly]methyl]thio]-[USP Convention. The United States Pharmacopeia 23/NF18. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates), p. 651]
Section 4: First-Aid Measures
Section 5: Fire-Fighting Measures
Section 6: Accidental Release Measures
Section 7: Handling and Storage
Section 8: Exposure Controls/Personal Protection
Section 9: Physical and Chemical Properties
White to pale yellow crystals[PDR; Physicians Desk Reference. 50th. 1996. Montvale,NJ: Medical Economics Co p. 1722 (1996)]
163-164 deg C[Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 617]
337.43[Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 617]
logP = -0.57, measured at pH 9.2[Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995., p. 49]
Solubility at 20 deg C (% w/v): 80 in DMF; 50 in acetic acid; 0.3 in methanol; 0.1 in water; <0.01 in ethanol, ethyl acetate, chloroform[Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 617]
Freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol.[PDR; Physicians Desk Reference. 50th. 1996. Montvale,NJ: Medical Economics Co p. 1722 (1996)]
Section 10: Stability and Reactivity
Section 11: Toxicological Information
All references are peer reviewed